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Variability of postnatal ossification timing and evidence for a “dosage” effect

✍ Scribed by Stanley M. Garn; Lawrence D. McCreery

Book ID
101457973
Publisher
John Wiley and Sons
Year
1970
Tongue
English
Weight
486 KB
Volume
32
Category
Article
ISSN
0002-9483

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✦ Synopsis

Although absolute variability in postnatal ossification timing is gen-eraIly larger in boys than in girls, reIative, conception-corrected variability is signscantly larger in girls, suggestive of a "dosage" effect and consistent with the hypothesis of partial X-linkage. These findings, together with the excess of sister-sister over brother-brother timing similarities are inconsistent with the hypothesis of selective inactivation of either the paternal or the maternal X chromosome.

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