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Variability of inversion of (R)-flurbiprofen in different species

✍ Scribed by Sabine Menzel-Soglowek; Gerd Geisslinger; Winfried S. Beck; Kay Brune


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
371 KB
Volume
81
Category
Article
ISSN
0022-3549

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Studies on the in vitro inversion of flu
✍ Anna Lombard; Valeria Rossetti; Maria Chiara Cassone πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 120 KB πŸ‘ 2 views

This paper reports in vitro studies on the metabolic inversion of flurbiprofen (FL), an arylpropionic acid antiinflammatory agent (2-APA). The inversion was studied with both rac-FL and R-FL, by incubation with rat hepatic microsomes, in the presence of either CoASH and ATP or NADPH. The two isomers