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Variability in nifedipine pharmacokinetics and dynamics: A new oxidation polymorphism in man

โœ Scribed by C.H. Kleinbloesem; P. van Brummelen; H. Faber; M. Danhof; N.P.E. Vermeulen; D.D. Breimer

Book ID
115777459
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
257 KB
Volume
33
Category
Article
ISSN
0006-2952

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The plasma concentration and cumulative urinary excretion over 34h of dextromethorphan, free and conjugated dextrorphan, and 3-hydroxymorphinan were determined in seven healthy Japanese subjects after oral administration of 30mg dextromethorphan hydrobromide. Conjugated metabolites were extensively