Value of tumor-antigen (TA-4) of squamous cell carcinoma in predicting the extent of cervical cancer
โ Scribed by Hiroshi Kato; Hitoshi Morioka; Haruyo Tsutsui; Shojiro Aramaki; Tadashi Torigoe
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 296 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0008-543X
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Background. Prognosis of head and neck squamous cell carcinoma (HNSCC) is strongly associated with cervical lymph node metastasis. Cathepsin-D is a lysosomal protease expressed in all cells. Its role in extracellular matrix degradation is postulated to promote tumor invasion and metastasis. Increase
The serum level of tumor-antigen 4 (TA-4) was measured in 401 patients with squamous cell carcinoma (SCC) of various organs (76 lung, 82 esophagus, and 234 head and neck). The mean serum level of TA-4 in patients with lung SCC was 3.6 times higher than that in healthy controls and even higher in the
Our aim was to evaluate the clinical usefulness of serum concentrations of squamous-cell carcinoma antigen (SCC-Ag) and tissue polypeptide antigen (TPA) in the follow-up of patients with vulvar cancer. We measured SCC-Ag and TPA in 480 serum samples of 82 patients with squamous-cell vulvar cancer. R
Purpose. Pretreatment CT volumetric measurement of the primary tumor has been shown to be a predictor of local control in patients with laryngeal carcinoma treated with radiation therapy (RT) alone. A direct association has been demonstrated between tumor volume of supraglottic squamous cell carcino