Value of distal compound muscle action potential duration prolongation in acute inflammatory demyelinating polyneuropathy: A European perspective

✍ Scribed by Yusuf A. Rajabally; Guillaume Nicolas

• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: English
• Weight: 81 KB
• Volume: 43
• Category: Article
• ISSN: 0148-639X
• DOI: 10.1002/mus.21974

✦ Synopsis

Abstract

Introduction: The value of distal compound muscle action potential duration (DCMAPD) has not been widely studied in acute inflammatory demyelinating polyneuropathy (AIDP) with electromyography (EMG) equipment at low‐cut filter settings <10 Hz, as used in Europe. Methods: We retrospectively reviewed the records of 40 patients with AIDP and 40 controls with axonal neuropathy, from Leicester, UK, and Angers, France. Results: The best combination of sensitivity/specificity for AIDP using DCMAPD prolongation in any one nerve was offered by cut‐offs from two other studies (sensitivity: 90% and 87.5%, respectively; specificity: 92.5% for both). Independent DCMAPD prolongation in any one nerve was better than, or equivalent to, other criteria. Conclusions: DCMAPD prolongation in any one nerve, at cut‐offs suggested by prior studies, represents a sensitive and specific marker to aid/simplify electrodiagnosis of AIDP in patients studied with EMG equipment with low‐cut filter settings of <10 Hz. Muscle Nerve, 2011