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Valproic acid stimulates clusterin expression in human astrocytes: Implications for Alzheimer's disease

โœ Scribed by Tapio Nuutinen; Tiina Suuronen; Anu Kauppinen; Antero Salminen


Book ID
116772164
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
409 KB
Volume
475
Category
Article
ISSN
0304-3940

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## Abstract Autophagosomes are accumulated in Alzheimer's disease (AD), but the regulatory pathway of autophagy in AD remains largely unknown. By using electron microscopy, Western blotting, and immunocytochemistry, here we show that autophagosomes are accumulated in rat neurons by okadaic acid (OA