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Valproic acid inhibits the depolarizing rectification in neurons of rat amygdala

✍ Scribed by L.-M. Tian; K.A. Alkadhi

Book ID
117187786
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
843 KB
Volume
33
Category
Article
ISSN
0028-3908

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Valproic acid (WA) is an anticonvulsant agent which produced marked choleresis in the rat. Bile flow rate increased from 50 to 60 pl per min per kg to 120 to 145 p1 per min per kg immediately after i.v. injection of VPA (37.5 to 150 mg per kg; 2 ml per kg) in male Sprague-Dawley rats. The duration o