## Abstract Holoprosencephaly (HPE) and craniosynostosis are separate conditions that have occasionally been observed to occur simultaneously in the same patient. Here, we compile patients with both conditions who have been documented in the literature thus far; moreover, we report on two additiona
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Valproic acid embryopathy: Report of two siblings with further expansion of the phenotypic abnormalities and a review of the literature
โ Scribed by Kozma, Chahira
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 250 KB
- Volume
- 98
- Category
- Article
- ISSN
- 0148-7299
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Trisomy 16 is the most frequent autosomal anomaly seen in early spontaneous abortions, accounting for 15 per cent of all chromosomally abnormal early spontaneous abortions. This trisomy is thought to be lethal in the non-mosaic state and incompatible with full fetal development. We report a case of