Valproate-induced hyperammonemia in juvenile ceroid lipofuscinosis (Batten disease)
✍ Scribed by Larsen, Erling P.; Østergaard, John R.
- Book ID
- 122330987
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 259 KB
- Volume
- 23
- Category
- Article
- ISSN
- 1059-1311
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📜 SIMILAR VOLUMES
Batten disease, or the juvenile form of neuronal ceroid lipofuscinosis, is an autosomal recessive neurodegenerative disorder manifesting with progressive blindness, seizures, and dementia, leading to an early death. The CLN3 locus which is involved in Batten disease had been localized to chromosome
The human hereditary ceroid-lipofuscinoses are a group of autosomal recessively inherited diseases characterized by massive accumulations of autofluorescent lysosomal storage bodies in the cells of many tissues and by neuronal degeneration throughout the central nervous system. There are a number of