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Valine-alanine manganese superoxide dismutase polymorphism is not associated with alcohol-induced oxidative stress or liver fibrosis

โœ Scribed by Stephen F. Stewart; Julian B. Leathart; Yuanneng Chen; Ann K. Daly; Roberta Rolla; Daria Vay; Elisa Mottaran; Matteo Vidali; Emanuele Albano; Chris P. Day

Book ID
118686822
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
145 KB
Volume
36
Category
Article
ISSN
0270-9139

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Valine-alanine manganese superoxide dism
Valine-alanine manganese superoxide dismutase polymorphism is not associated with alcohol-induced oxidative stress or liver fibrosis
โœ Stephen F. Stewart; Julian B. Leathart; Yuanneng Chen; Ann K. Daly; Roberta Roll ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 680 KB

The role of genetic factors in the pathogenesis of alcohol-induced liver disease (ALD) is receiving increasing attention. Recently, it has been reported that homozygosity for a valine to alanine substitution in the mitochondrial targeting sequence of manganese superoxide dismutase (Mn-SOD) represent