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Validity of sampling error as a cause of noncorrelation

โœ Scribed by Hearp, Matthew L. ;Locante, Alberto M. ;Ben-Rubin, Michelle ;Dietrich, Ruth ;David, Odile

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
95 KB
Volume
111
Category
Article
ISSN
0008-543X

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โœฆ Synopsis

BACKGROUND. Sampling error is a common explanation of noncorrelation in women whose Papanicolaou (Pap) tests show high-grade intraepithelial lesions (HSIL) but whose follow-up cervical biopsies show only cervical intraepithelial neoplasia (CIN) 1, koilocytosis, or reactive/inflammatory changes. The purpose of this study was to demonstrate the validity of sampling error in this setting by determining the proportion of negative colposcopic cervical biopsies in women with HSIL who subsequently undergo cone/loop electrode excision procedure (LEEP) biopsies or repeat cervical biopsies that confirm the diagnosis of highgrade CIN (HGCIN).

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