The effect of prostacyclin on canine hepatic bile flow was evaluated. Utilizing chronic, unanesthetized bile fistula dogs, prostacyclin was found to significantly increase bile flow rates and bile bicarbonate and cyclic AMP concentration and output when compared to control values. The choleretic res
Validation of viscosity measurements for canine hepatic bile
β Scribed by David D. Wilson; Howard S. Lowensohn
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 417 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0270-9139
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β¦ Synopsis
This study developed the validated standards for a known viscosity method by obtaining consistent viscosity measurements with defined precision, reproducibility and sensitivity limits for canine hepatic bile. Size 76 Cannon-Manning semimicro viscometers yielded the most precise viscosity measurements. With the development of proper handling methods for fresh bile samples, a precision defined by a coefficient of variation of ~* 0 . 3 % was obtained. To maintain viscometer constancy, the viscometers must be cleaned with chromic acid after each bile test and pass reproducibility tests using defined distilled water viscosity tests.
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