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Validation of transgenic mice harboring the human prototype c-Ha-ras gene as a bioassay model for rapid carcinogenicity testing

โœ Scribed by Satoshi Yamamoto; Koji Urano; Tatsuji Nomura


Book ID
119539695
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
75 KB
Volume
102-103
Category
Article
ISSN
0378-4274

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To determine if hemizygous transgenic mice carrying the human c-Ha-ras gene (CB6F1-Tg Hras2 mice (Hras2 mice)) are susceptible to the carcinogenic potential of known murine carcinogens, male and female Hras2 mice and their non-transgenic CB6F1 littermates (non-Tg mice) were each given a single intra