Validation of the first commercial ELISA for type 2N von Willebrand’s disease diagnosis
✍ Scribed by A. VEYRADIER; C. CARON; C. TERNISIEN; M. WOLF; M. TROSSAERT; E. FRESSINAUD; J. GOUDEMAND
- Book ID
- 108775724
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 277 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1351-8216
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📜 SIMILAR VOLUMES
## Diagnosis of von Willebrand disease Type 2N (vWD 2N ), which mimics hemophilia A and its carrier state, is important for accurate genetic counseling and appropriate therapy. To make testing for the disorder more clinically applicable, we developed a simplified method for measurement of factor V
## Abstract Most of type 2A von Willebrand disease (VWD) mutations are clustered within the A2 domain of VWF, encoded by the 3′ region of exon 28 of the von Willebrand factor (VWF) gene. A patient with lifelong and severe bleeding diathesis and laboratory data of type 2A VWD is described. The analy