Validation of surrogate endpoint biomarkers in prostate cancer chemoprevention trials
โ Scribed by Bruce J Trock
- Book ID
- 117263395
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 210 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0090-4295
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Surrogate biomarkers for risk assessment and efficacy of potential chemopreventive agents are needed to improve the efficiency and reduce the cost of conducting chemoprevention trials. In addition to criteria of sensitivity, specificity, quantifiability, and reproducibility applicable to most potent
The most efficient strategy for chemoprevention clinical trials are short-term studies which focus on surrogate endpoint biomarkers (SEBs) in high-risk target populations. High-grade prostatic intraepithelial neoplasia (PIN) is the most likely precursor of prostate cancer, and is found in a signific