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Validation of AAV-mediated gene targeting

โœ Scribed by Russell, David W.; Hirata, Roli K.; Inoue, Naoki


Book ID
118675921
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
404 KB
Volume
20
Category
Article
ISSN
1087-0156

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Various regions of the brain have been successfully transduced by recombinant adeno-associated virus (rAAV) vectors with no detected toxicity. When using the cytomegalovirus immediate early (CMV) promoter, a gradual decline in the number of transduced cells has been described. In contrast, the use o