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Validation of a new screening, determinative, and confirmatory multi-residue method for nitroimidazoles and their hydroxy metabolites in turkey muscle tissue by liquid chromatography-tandem mass spectrometry

✍ Scribed by Joe O. Boison; Philip A. Asea; Johanna L. Matus

Book ID
118283271
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
323 KB
Volume
4
Category
Article
ISSN
1942-7603

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An SPE-LC-MS/MS method was developed, validated and applied to the determination of nicotine and five major metabolites in human urine: cotinine, trans-3'-hydroxycotinine, nicotine-N-glucuronide, cotinine-N-glucuronide and trans-3'-hydroxycotinine-O-glucuronide. A 500 microL urine sample was pH-adju