Validation of a method for quantifying enzalutamide and its major metabolites in human plasma by LC–MS/MS
✍ Scribed by Bennett, Daniel; Gibbons, Jacqueline A; Mol, Roelof; Ohtsu, Yoshiaki; Williard, Clark
- Book ID
- 123617203
- Publisher
- Future Science
- Year
- 2014
- Tongue
- English
- Weight
- 888 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1757-6180
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract A simple, rapid and sensitive liquid chromatography–tandem mass spectroscopy (LC–MS/MS) method was developed and validated for the determination of ethyl gallate, a pharmacologically active constituent isolated from __Lagerstroemia speciosa__ (Linn.) Pers. This method was used to examin
## Abstract The anticancer drug capecitabine and its metabolites [including the active metabolite 5‐fluorouracil (5‐FU)] display high pharmacokinetic inter‐patient variability. Such variability, which may lead to treatment failure or toxicity, could need drug concentration measurement to individual
An analytical method based on liquid–liquid extraction has been developed and validated for analysis of agomelatine in human plasma. Fluoxetine was used as an internal standard for agomelatine. A Betasil C18 (4.0 × 100 mm, 5 µm) column provided chromatographic separation of analytes followed by dete