✦ LIBER ✦

Validation of a fully automated hippocampal segmentation method on patients with dementia

✍ Scribed by Michael J. Firbank; Robert Barber; Emma J. Burton; John T. O'Brien

Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 292 KB
Volume: 29
Category: Article
ISSN: 1065-9471
DOI: 10.1002/hbm.20480

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

We describe a fully automated method for hippocampal segmentation. The method uses SPM5 (http://www.fil.ion.ucl.ac.uk/spm/) software to segment the brain into grey/white matter, and spatially normalize the images to standard space. Grey matter pixels within a predefined hippocampal region in standard space are identified to segment the hippocampi. The method was validated on 36 subjects (9 each of Alzheimer's disease, dementia with Lewy bodies, vascular dementia, and healthy controls). The mean absolute difference in volume compared with manual segmentation was 11% (SD 9%). Linear regression between manual and automated volume gave V(auto) = V(manual) × 0.83 + 401 ml. The method provides an acceptable automated alternative to manual segmentation which may be of value in large studies. Hum Brain Mapp 2008. © 2007 Wiley‐Liss, Inc.

📜 SIMILAR VOLUMES

Validation of hippocampal volumes measur

Validation of hippocampal volumes measured with one manual and two automated methods using FreeSurfer and IBASPM in chronic major depressive disorder

✍ Woo Suk Tae; Sam Soo Kim; Kang Uk Lee; Eui-Cheol Nam; Keun Woo Kim 📂 Article 📅 2009 🏛 Springer 🌐 English ⚖ 67 KB

Automated segmentation of the aorta from

Automated segmentation of the aorta from phase contrast MR images: Validation against expert tracing in healthy volunteers and in patients with a dilated aorta

✍ Alain Herment; Nadjia Kachenoura; Muriel Lefort; Mourad Bensalah; Anas Dogui; Fr 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 724 KB

## Abstract ## Purpose: To assess if segmentation of the aorta can be accurately achieved using the modulus image of phase contrast (PC) magnetic resonance (MR) acquisitions. ## Materials and Methods: PC image sequences containing both the ascending and descending aorta of 52 subjects were acqui