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Validation of a biophysical drug absorption model by the PATQSAR system

✍ Scribed by Marival Bermejo; Virginia Merino; Teresa M. Garrigues; Jose M. Pla Delfina; Antonio Mulet; Patrick Vizet; Gérard Trouiller; Christiane Mercier

Book ID
111522807
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
508 KB
Volume
88
Category
Article
ISSN
0022-3549

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## Abstract A model was developed for predicting the influence of cyclodextrins (CDs) delivered as a physical mixture with drug on oral absorption. CDs are cyclic oligosaccharides which form inclusion complexes with many drugs and are often used as solubilizing agents. The purpose of this work is t