Validation crisis in animal models of drug addiction: Beyond non-disordered drug use toward drug addiction

Extinction of drug- and withdrawal-paire

Extinction of drug- and withdrawal-paired cues in animal models: Relevance to the treatment of addiction

✍ Karyn M. Myers; William A. Carlezon Jr. 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 429 KB

Conditioned drug craving and withdrawal elicited by cues paired with drug use or acute withdrawal are among the many factors contributing to compulsive drug taking. Understanding how to stop these cues from having these effects is a major goal of addiction research. Extinction is a form of learning