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Valdecoxib, a non-steroidal anti-inflammatory drug

✍ Scribed by Malathy Sony, S. M. ;Charles, P. ;Ponnuswamy, M. N. ;Yathirajan, H. S.

Publisher
International Union of Crystallography
Year
2004
Tongue
English
Weight
405 KB
Volume
61
Category
Article
ISSN
1600-5368

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✦ Synopsis

benzenesulfonamide], C 16 H 14 N 2 O 3 S, a diaryl-substituted isoxazole, is a non-steroidal anti-in¯ammatory drug (NSAID) that is used for the treatment of rheumatoid arthritis, osteoarthritis and dysmenorrhea pain. The planar isoxazole ring is oriented at angles of 22.2 (1) and 54.3 (1) with respect to the phenyl and benzenesulfonamide groups, respectively. NÐHÁ Á ÁO and CÐHÁ Á ÁO hydrogen bonds and NÐHÁ Á Á%, CÐHÁ Á Á% and %±% interactions stabilize the crystal packing.

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