✦ LIBER ✦

Vaginal melanoma and the role of regional chemotherapy

✍ Scribed by Dr. Mansoor H. Beg; James H. Muchmore; R. Davilene Carter; Edward T. Krementz

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 291 KB
Volume: 53
Category: Article
ISSN: 0022-4790
DOI: 10.1002/jso.2930530217

No coin nor oath required. For personal study only.

✦ Synopsis

Vaginal melanoma is a rare cancer usually diagnosed as a locally advanced disease. Aggressive surgical management of the primary tumor and localregional recurrences, combined with the use of adjuvant radiation and chemotherapy, improves disease-free interval and, perhaps, survival times. Techniques of regional chemotherapy allow the delivery of high doses of chemotherapy to the tumor bed, while minimizing systemic toxicities. These treatments can be used to decrease tumor size, render bulky tumors resectable, and decrease the need for radical procedures. Additionally, they may help eradicate clinically inapparent local-regional disease and have a favorable effect on survival times.

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