VAD protocol for treatment of advanced refractory multiple myeloma
β Scribed by Scheithauer, W. ;Cortelezzi, A. ;Kutzmits, R. ;Baldini, L. ;Ludwig, H.
- Publisher
- Springer-Verlag
- Year
- 1987
- Weight
- 425 KB
- Volume
- 55
- Category
- Article
- ISSN
- 1432-0584
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Sixteen patients with multiple myeloma refractory to alkylating agents were treated with vincristine 0.25 mg/m2 i.v. on days 1 to 4 and prednisone 1 gm/m2 on days 1 and 3. Chemotherapy was repeated every 2 weeks. Of 15 evaluable patients, five achieved a partial response and four stable disease. Thr
We evaluated possible prognostic factors just before salvage therapy with vincristine, doxorubicin, and dexamethasone (VAD) for 36 patients with refractory multiple myeloma. The median duration from diagnosis to the first VAD salvage was 14 months (range 2-76 months). Among parameters that have been