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Vaccines: Self-amplifying RNA in lipid nanoparticles: a next-generation vaccine?

โœ Scribed by Flemming, Alexandra

Book ID
115521170
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
145 KB
Volume
11
Category
Article
ISSN
1474-1776

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In vivo evidence of oral vaccination wit
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โœ Federica Sarti; Glen Perera; Fabian Hintzen; Katerina Kotti; Vassilis Karageorgi ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 474 KB

Although oral vaccination has numerous advantages over the commonly used parenteral route, degradation of vaccine and its low uptake in the lymphoid tissue of the gastrointestinal (GI) tract still impede their development. In this study, the model antigen ovalbumin (OVA) and the immunostimulant mono