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Vaccine Protection of Chimpanzees Against Challenge with HIV-1-Infected Peripheral Blood Mononuclear Cells

✍ Scribed by Fultz, P. N.; Nara, P.; Barre-Sinoussi, F.; Chaput, A.; Greenberg, M. L.; Muchmore, E.; Kieny, M.-P.; Girard, M.


Book ID
121151914
Publisher
American Association for the Advancement of Science
Year
1992
Tongue
English
Weight
215 KB
Volume
256
Category
Article
ISSN
0036-8075

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## Abstract This study was undertaken to evaluate and compare the susceptibility of chimpanzee versus human peripheral blood mononuclear cells (PBMCs) to infection with SIVcpz and HIV‐1 non‐syncitium inducing primary isolates. The results demonstrate clearly that chimpanzee PBMCs have a lower capac