Vaccine-induced antibodies to native and recombinant human immunodeficiency virus type 1 envelope glycoproteins
β Scribed by Geoffrey J. Gorse; Sharon E. Frey; Gira Patel; Frances K. Newman; Robert B. Belshe; NIAID AIDS Vaccine Clinical Trials Network
- Book ID
- 119151978
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 771 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0264-410X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## Background A monoclonal antibody (mAb) 2F5 binds to the membraneβproximal external region (MPER) of the transmembrane subunit gp41 of human immunodeficiency virus type 1 (HIVβ1) is known to broadly neutralize HIVβ1 strains. The Adenovirus type 5 vector (Ad5) has been widely applied
## Abstract A blocking ELISA was developed to confirm the specificity of screening tests for antiβHIVβ1 antibodies. A murine monoclonal antibody (McAb) raised against recombinant gp 160 was used in combination with a commercial technique (ELAVIAβ1). After determining the optimal experimental condit