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Vaccination with BV8S2 protein amplifies TCR specific regulation and protection against experimental autoimmune encephalomyelitis in TCR BV8S2 transgenic mice

✍ Scribed by H. Offner; K. Adlard; B.F. Bebo Jr.; J. Schuster; G.G. Burrows; A.C. Buenafe

Book ID
117337835
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
132 KB
Volume
90
Category
Article
ISSN
0165-5728

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## Abstract To investigate regulatory mechanisms which naturally prevent autoimmune diseases, we adopted the genetically restricted immunodeficient (RAG‐1^βˆ’/βˆ’^) myelin basic protein (MBP)‐specific T cell receptor (TCR) double transgenic (T/Rβˆ’) mouse model of spontaneous experimental autoimmune ence