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V and C parts of immunoglobulin κ-chain genes are separate in myeloma

✍ Scribed by MATTHYSSENS, GASTON; TONEGAWA, SUSUMU


Book ID
109709914
Publisher
Nature Publishing Group
Year
1978
Tongue
English
Weight
375 KB
Volume
273
Category
Article
ISSN
0028-0836

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Allelic variants of rearranged immunoglo
✍ S. M. Deyev; D. N. Urakov; A. G. Stepchenko; O. L. Polanovsky 📂 Article 📅 1991 🏛 Springer Netherlands 🌐 English ⚖ 454 KB

The hybridoma PTF-02 secretes an antibody against pig transferrin. Rearranged genes for heavy and light immunoglobulin chains have been studied in the genomes of this hybridoma and in the parent myeloma P3-X63.Ag8.653. The hybridoma was shown to contain three rearranged allelic variants of the heavy