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Uveitopathogenic Site of the γ-Subunit of Cyclic Guanosine Monophosphate Phosphodiesterase in Lewis Rats

✍ Scribed by Mutsumi Matsunaga; Tohru Abe; Naoki Satoh; Ako Nakajima; Masatoshi Ohkoshi; Shozo Sakuragi


Book ID
114044286
Publisher
Springer
Year
2001
Tongue
English
Weight
617 KB
Volume
45
Category
Article
ISSN
0021-5155

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A possible defect of guanosine 3Ј-5Ј-cyclic monophosphate (cGMP) content in the renal tissue caused by an increased activity of cGMP phosphodiesterase (PDE) has, so far, not been evaluated in the pathogenesis of renal resistance to endogenous natriuretic peptides (ENP) in cirrhosis with ascites. To