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UV resonance Raman studies of quaternary structure changes of human hemoglobin using a tyrosine α42 mutant

✍ Scribed by M. Nagai; K. Imai; S. Kaminaka; Y. Mizutani; T. Kitagawa


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
87 KB
Volume
59
Category
Article
ISSN
0162-0134

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## Abstract The deoxy‐form of human adult hemoglobin (Hb A) exhibits a distinct negative CD band at 287 nm that disappears in the oxy‐form. It has been suggested that the negative CD band is due to the environmental alteration of Tyr‐α42 or Trp‐β37 at the α~1~β~2~ contact upon deoxygenation. To eva