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UV-induced DNA damage in carcinogenesis and its repair

✍ Scribed by Nishigori, Chikako


Book ID
119562855
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
70 KB
Volume
23
Category
Article
ISSN
0923-1811

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Ultraviolet light (UV) is thought to have had a major impact on the early evolution of life. UV is absorbed by nucleic acids and produces several types of DNA damage, which interfere with DNA replication and transcription. This damage can result in mutagenesis and cell killing. Several mechanisms fo