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UTP and mechanical stimulation induce ATP release from osteocytes.

✍ Scribed by T.M. Kringelbach⁎; I. Novak; L.F. Bonewald; O. Vang; P. Schwarz; N.R. Jørgensen

Book ID
119204169
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
69 KB
Volume
50
Category
Article
ISSN
8756-3282

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## Abstract Mechanical loads are required for optimal bone mass. One mechanism whereby mechanical loads are transduced into localized cellular signals is strain‐induced fluid flow through lacunae and canaliculi of bone. Gap junctions (GJs) between osteocytes and osteoblasts provides a mechanism whe