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Utilization of Site-Specific Recombination for Generating Therapeutic Protein Producing Cell Lines

✍ Scribed by Margie Campbell; Susanne Corisdeo; Clair McGee; Denny Kraichely


Book ID
107581809
Publisher
Humana Press Inc
Year
2010
Tongue
English
Weight
249 KB
Volume
45
Category
Article
ISSN
1073-6085

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## Abstract ## Background The adenovirus 14.3 kDa hexon‐associated protein IX (pIX) functions in the viral capsid as ‘cement’ and assembles the hexons in stable groups‐of‐nine (GONs). Although viruses lacking pIX do not form GONs, and are less heat‐stable than wild‐type (wt) viruses, they can be p