A8 an alternative to the use of dibenzyl and di-&-butyl phosphorohalidates for the phosphorylation of alcohols.1-3 our reoent studies have ooncentrated on the use of dialkyl &&diethylphosphoramidites for the efficient phosphorylation OP alcohols and hydroxycontaining biomoleoules. In particular, we
β¦ LIBER β¦
Utilization of O-xylylene N,N-diethylphosphoramidite for the synthesis of phosphoric diesters
β Scribed by Yutaka Watanabe; Yasunobu Komoda; Shoichiro Ozaki
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- French
- Weight
- 263 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
o-Xylylene alkyl phosphites which were derived by the reaction of alcohols with o-xylylene N,Ndiethylphosphommidite in the presence of IrI-tetrazole wcrc reacted with second alcohols in the presence of pyridinium bromide perbromide, and a letiamine, to give the corresponding triesters involving phospholipids. The esters were deprotected to phosphoric diesters by hydrogcnolysis or the reaction with d&odium disulfide.
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## Abstract For Abstract see ChemInform Abstract in Full Text.