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Utilization of Methyl 3-Aryl-2-thiocyanatopropanoates in the Synthesis of 2-(4-Morpholinyl)- and 2-(Piperazinyl)-5-(benzyl)thiazol-4-ones 1

✍ Scribed by Obushak, Mykola D.; Karpyak, Volodymyr V.; Ostapiuk, Yuri V.; Matiychuk, Vasyl S.

Book ID: 121258359
Publisher: Taylor and Francis Group
Year: 2007
Tongue: English
Weight: 209 KB
Volume: 182
Category: Article
ISSN: 1042-6507
DOI: 10.1080/10426500701242103

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## Abstract magnified image A new method for the synthesis of substituted 5‐(2‐hydroxyethyl)‐2‐phenylimino‐1,3‐thiazolidin‐4‐ones and 5‐(2‐hydroxyethyl)‐2‐phenylamino‐4,5‐dihydro‐1,3‐thiazol‐4‐ones is described, starting from phenylthioureas and 3‐bromotetrahydrofuran‐2‐one. The reaction proceeds