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Utility of Toxicogenomics in Risk Assessment of Human Carcinogens: A Case Study on Benzo(a)pyrene

✍ Scribed by Chepelev, Nikolai L.; Moffat, Ivy D.; Labib, Sarah; Bourdon, Julie; Kuo, Byron; Buick, Julie; Lemieux, France; Malik, Amal; Halappanavar, Sabina; Yauk, Carole L.

Book ID
123105651
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
166 KB
Volume
53
Category
Article
ISSN
0891-5849

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## Abstract Metabolism of the carcinogenic hydrocarbon benzo(a)pyrene (BP) to water and alkali‐soluble products was measured in cultured fibroblast and epithelial cells from human embryos. The alkali‐soluble products represented only a small fraction of BP metabolism. Fibroblasts from different org