A total of 41 patients with chronic hepatitis C virus (HCV) defined as abnormal liver injury test results for 6 months or more and HCV RNA positivity in plasma were studied to determine if the liver might not be the only focus of HCV infection in individuals treated with interferon alfa (IFN-a). AU
Utility of hepatitis C virus RNA determinations in hepatic tissue as an end point for interferon treatment of chronic hepatitis C
โ Scribed by GURAKAR, A
- Book ID
- 121968941
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 421 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0270-9139
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Hepatitis C virus RNA as detected by reverse transcription and nested polymerase chain reaction was monitored in 16 patients with chronic hepatitis C treated with interferon. Hepatitis C virus R N A became undetectable after 4 to 8 wk of interferon administration in 13 of the 16 patients. During 6 m
The extent of extrahepatic hepatitis C virus (HCV) replication seems to be low-level and confined to cells of hematopoietic lineage. However, given the spectrum of extrahepatic manifestations associated with HCV, several tissues other than the liver have been suggested as targets of HCV replication