Utility of cytokeratin 20 and Ki-67 as markers of urothelial dysplasia
β Scribed by Lakshmi P. Kunju; Cheryl T. Lee; James Montie; Rajal B. Shah
- Book ID
- 115175505
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 730 KB
- Volume
- 55
- Category
- Article
- ISSN
- 1320-5463
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π SIMILAR VOLUMES
Background. Suprabasal expression of Ki-67 is assessed as a marker for oral dysplasia. The study involved nonneoplastic epithelium adjacent to 74 oral squamous cell carcinomas. Methods. An immunohistochemical technique was carried out (peroxidase-antiperoxidase) with the monoclonal antibody MIB-1.
The differentiation of epithelial tumors arising in the kidney (urothelial vs. renal cell carcinoma) sometimes can be difficult by clinical and radiologic studies. Because urothelial and renal epithelium express unique cytokeratin (CK) 7 and 20 profiles, the authors studied the utility of these mark