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Utility of a 2-aminothiophene-3-carboxamide in the synthesis of thienopyridines and thienopyrimidines

✍ Scribed by Rafat M. Mohareb; Sherif M. Sherif; Hatem M. Gaber; Sami S. Ghabrial; Susan I. Aziz

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
121 KB
Volume
14
Category
Article
ISSN
1042-7163

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✦ Synopsis

Abstract

2‐Amino‐4,5,6,7‐tetrahydrobenzo[b]‐ thiophene‐3‐carboxamide (1) was prepared according to Gewald procedure. Its reactivity toward a variety of chemical reagents was studied to give thienopyridines and ‐pyrimidines. Β© 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:459–467, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10179

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