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Utility of 3-amino-4,6-dimethyl-1H-pyrazolo[3,4-b]pyridine in heterocyclic synthesis

✍ Scribed by Moustafa A. Gouda


Publisher
Journal of Heterocyclic Chemistry
Year
2010
Tongue
English
Weight
310 KB
Volume
48
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

This review describe the synthesis and reactions of 3‐amino‐4,6‐dimethyl‐1__H__‐pyrazolo[3,4‐b]pyridine as building block for the synthesis of polyfunctionalized heterocyclic compounds with pharmacological interest. J. Heterocyclic Chem., 2011.


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## Abstract magnified image A series of pyrazolo[3,4‐__b__]pyridines has been synthesized by __Friedländer__ condensation of 5‐amino‐pyrazole‐4‐carbaldehyde **1** with active methylene compounds in basic medium. Pyrazolo[4′3′:5,6]pyrido‐[2,3‐__d__]pyrimidines have been synthesized from pyrazolo[3,