Germ-line mutations in BRCA1 or BRCA2 in
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Patricia A. Mote; Jennifer A. Leary; Kelly A. Avery; Kerstin Sandelin; Georgia C
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Article
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2004
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John Wiley and Sons
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English
⚖ 177 KB
👁 1 views
## Abstract The breast cancer susceptibility genes __BRCA1__ and __BRCA2__ are responsible for a large proportion of familial breast and ovarian cancer, yet little is known of how disruptions in the functions of the proteins these genes encode increased cancer risk preferentially in hormone‐depende