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Ustekinumab, a human interleukin 12/23 monoclonal antibody, for psoriatic arthritis: randomised, double-blind, placebo-controlled, crossover trial

✍ Scribed by Alice Gottlieb; Alan Menter; Alan Mendelsohn; Yaung-Kaung Shen; Shu Li; Cynthia Guzzo; Scott Fretzin; Rod Kunynetz; Arthur Kavanaugh


Book ID
117304280
Publisher
The Lancet
Year
2009
Tongue
English
Weight
175 KB
Volume
373
Category
Article
ISSN
0140-6736

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## Abstract ## Objective Interleukin‐6 (IL‐6) is a pleiotropic cytokine that regulates the immune response, inflammation, and hematopoiesis. Overproduction of IL‐6 plays pathologic roles in rheumatoid arthritis (RA), and the blockade of IL‐6 may be therapeutically effective for the disease. This s

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