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Using yeast to place human genes in functional categories

✍ Scribed by Nianshu Zhang; Michael Osborn; Paul Gitsham; Kuangyu Yen; J.Ross Miller; Stephen G Oliver


Book ID
117521181
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
358 KB
Volume
303
Category
Article
ISSN
0378-1119

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One possible route to the evaluation of gene function is a quantitative approach based on the concepts of metabolic control analysis (MCA). An important first step in such an analysis is to determine the effect of deleting individual genes on the growth rate (or fitness) of S. cerevisiae. Since the