✦ LIBER ✦

Using Variability to Regulate Long Term Biological Rhythms

✍ Scribed by Troy Shinbrot; Kathryn Scarbrough

Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 273 KB
Volume: 196
Category: Article
ISSN: 0022-5193
DOI: 10.1006/jtbi.1998.0843

No coin nor oath required. For personal study only.

✦ Synopsis

We present a model for the generation of precise, long term rhythms from a collection of imprecise, short term oscillators. The model uses variability between oscillators in conjunction with simple coupling rules to produce long term rhythms that are independent of rate equations (e.g. Arrhenius). The rhythms generated by the model are controlled by only two independent parameters and exhibit several physiologically interesting properties, including ready entrainment to external signals and splitting in response to strong constant signals. The model provides several predictions that can be tested in future experiments.

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