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Using the Noninformative Families in Family-Based Association Tests: A Powerful New Testing Strategy

✍ Scribed by Christoph Lange; Dawn DeMeo; Edwin K. Silverman; Scott T. Weiss; Nan M. Laird


Book ID
117854306
Publisher
American Society of Human Genetics
Year
2003
Tongue
English
Weight
158 KB
Volume
73
Category
Article
ISSN
0002-9297

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## Abstract We propose a new multimarker test for family‐based studies in candidate genes. We use simulations under different genetic models to assess the performance of competing testing strategies, characterized in this study as combinations of the following important factors: genes, statistical