Using the Model-Free Approach to Interpret 13C NMR Multiplet Relaxation Data from Peptides and Proteins

Estimation of Dynamic Parameters from NM

Estimation of Dynamic Parameters from NMR Relaxation Data using the Lipari–Szabo Model-Free Approach and Bayesian Statistical Methods

✍ Michael Andrec; Gaetano T. Montelione; Ronald M. Levy 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 206 KB

In order to analyze NMR relaxation data in terms of parameters which describe internal motion, one must first obtain a description of the overall tumbling of the macromolecule in solution. Methods currently used to estimate these global parameters may not always provide reliable estimates of their v