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Using PRINS for gene mapping in polytene chromosomes

✍ Scribed by Harvest F. Gu; Maria I. Lind; Lars Wieslander; Ulf Landegren; Kenneth Soderhall; Ojar Melefors

Book ID
110370114
Publisher
Springer
Year
1997
Tongue
English
Weight
385 KB
Volume
5
Category
Article
ISSN
0967-3849

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Primed in situ labeling (PRINS) is a relatively new technology with wide-ranging applications in clinical cytogenetics. Using PRINS, we have identified the chromosomal origin of marker chromosomes in three patients. In the first patient with primary amenorrhea, we were able to confirm the marker chr