๐”– Bobbio Scriptorium
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Using mouse forward genetics to define novel target space

โœ Scribed by Nancy A. Hong; Steve A. Kay; Richard J. Glynne


Book ID
114410261
Publisher
Elsevier Science
Year
2002
Weight
289 KB
Volume
1
Category
Article
ISSN
1477-3627

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## Abstract ## Background Retargeting is necessary to overcome the limitations of adenovirus (Ad)โ€based gene therapy vectors. To this end, we previously constructed an adenovirus with the fiber knob domain replaced by a fibritin trimerization motif fused to the CD40 ligand (Ad5Luc.FF/CD40L). We de