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Using identity by descent estimation with dense genotype data to detect positive selection

✍ Scribed by Han, Lide; Abney, Mark


Book ID
121323566
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
921 KB
Volume
21
Category
Article
ISSN
1018-4813

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Identity by descent estimation with dens
✍ Lide Han; Mark Abney πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 255 KB

We present a novel method, IBDLD, for estimating the probability of identity by descent (IBD) for a pair of related individuals at a locus, given dense genotype data and a pedigree of arbitrary size and complexity. IBDLD overcomes the challenges of exact multipoint estimation of IBD in pedigrees of